An Electrospun Degradable Scaffold Based on a Novel Hydrophilic Polyester for Tissue-Engineering Applications (pages 1684–1692)
Hajar Seyednejad, Wei Ji, Wouter Schuurman, Wouter J. A. Dhert, Jos Malda, Fang Yang, John A. Jansen, Cornelus van Nostrum, Tina Vermonden and Wim E. Hennink
Article first published online: 19 SEP 2011 | DOI: 10.1002/mabi.201100229
It is shown that biodegradable fibrous scaffolds based on a novel functionalized polymer (pHMGCL) that is more hydrophilic than PCL possesses excellent properties in terms of degradation kinetics, processability via electrospinning, chondrocytes adhesion and differentiation. The results establish a basis for further implementation of this material in the field of cartilage tissue engineering.