Banded Spherulitic Morphology in Blends of Poly (propylene fumarate) and Poly(ϵ-caprolactone) and Interaction with MC3T3-E1 Cells

Authors

  • Kan Wang,

    1. Department of Materials Science and Engineering, The University of Tennessee, Knoxville, TN 37996, USA
    Search for more papers by this author
  • Stephen Jesse,

    1. Center for Nanophase Materials Science, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    Search for more papers by this author
  • Shanfeng Wang

    Corresponding author
    1. Department of Materials Science and Engineering, The University of Tennessee, Knoxville, TN 37996, USA
    2. Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    • Department of Materials Science and Engineering, The University of Tennessee, Knoxville, TN 37996, USA.
    Search for more papers by this author

Abstract

The thermal properties, morphological development, crystallization behavior, and miscibility of semicrystalline PCL and its 25, 50, and 75 wt% blends with amorphous PPF in spin-coated thin films crystallized at various crystallization temperatures (Tc) from 25 to 52 °C are investigated. The surface roughness of PPF/PCL (ϕPCL = 75%) films increases with increasing Tc and consequently the adsorption of serum proteins is also increased. No significant variance is found in surface hydrophilicity or in mouse MC3T3-E1 cell attachment, spreading, and proliferation on PPF/PCL (ϕPCL = 75%) films crystallized isothermally at 25, 37, and 45 °C, because of low ridge height, nonuniformity in structures, and PPF surface segregation.

Ancillary