Entropy numbers of operators acting between vector-valued sequence spaces are estimated using information about the coordinate mappings. To do this some new ideas of combinatorial type are used. The results are applied to give sharp two-sided estimates of the entropy numbers of some embeddings of Besov spaces. For instance, our main result allows us to give exact two-sided estimates of the entropy numbers of the natural embedding of in where Q = (0, 1)d; θ1, θ2, p1, p2 ∈ (0, ∞], when the condition 1/θ1 − 1/θ2 ≥ 1/p1 − 1/p2 > 0 is satisfied. This work enables us to construct an example showing that the behaviour under real interpolation of entropy numbers can be even worse than in the example of 7.