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Keywords:

  • catalysis;
  • flow reactors;
  • metathesis;
  • ROMP;
  • supports

Abstract

Thumbnail image of graphical abstract

The monolith-supported Grubbs–Hoveyda catalyst.

A ring-opening metathesis polymerization- (ROMP-) based monolith was synthesized using a Grubbs' first generation catalyst. The living termini were used for surface grafting of norborn-5-ene-2-ylmethyl hexafluoroglutarate. The free carboxylic acid groups of the graft polymer were converted into the corresponding silver salt and reacted with the Grubbs–Hoveyda catalyst [RuCl2([DOUBLE BOND]CH[BOND](2-iPrO[BOND])C6H4)(IMesH2)] (IMesH2 = 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene) to yield a stable heterogeneous version of this catalyst for use in ring-closing metathesis (RCM) under continuous flow conditions.