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Spiropyran-Conjugated Pluronic as a Dual Responsive Colorimetric Detector

Authors

  • Yeon Jeong Oh,

    1. Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
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  • Jeong A. Nam,

    1. Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
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  • Abdullah Al-Nahain,

    1. Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
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  • Sangkug Lee,

    1. Korea Institute of Industrial Technology, Republic of Korea
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  • Insik In,

    Corresponding author
    1. Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
    • Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea.
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  • Sung Young Park

    Corresponding author
    1. Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
    • Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
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Abstract

Novel spiropyran-conjugated Pluronic [polyethylene oxide (PEO)-b-polypropylene oxide (PPO)-b-polyethylene oxide (PEO)] micelles are developed as a new colorimetric detector showing photo- or thermo-switchable behavior. Facile conjugation of spiropyran to Pluronic was confirmed by 1H NMR, UV–Vis, and Fluorescence spectroscopy. A switchable photoluminescence is found depending on the irradiation with either UV or visible light, and temperature resulting from structural isomerization of spiropyran between spiropyran (SP) and merocyanine (MC) form. Cytotoxicity of the spiropyran-conjugated Pluronic (SP-PL) was evaluated following an MTT assay, whereas photo responsiveness of spiropyran within the micelles was determined by confocal laser scanning microscopy.

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