Thermoresponsive Organic–Inorganic Hybrid Large-Compound Vesicles

Authors

  • Bo Peng,

    1. Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100190, China
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  • Yongming Chen

    Corresponding author
    1. Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100190, China
    • Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100190, China.===

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Abstract

Herein, gelated thermoresponsive large-compound vesicles (LCVs) are reported for the first time. The LCVs are prepared by self-assembly of poly(ethylene oxide)-block-poly[N-isopropylacrylamide-random-3-(trimethoxysilyl)propyl methacrylate] [PEO-b-P(NIPAM-r-TMPM)] in DMF-water mixture. Then, sol-gel reaction of the reactive PTMPM block is performed to stabilize the LCVs. LCVs with higher cross-linking density keep almost the same size under different temperatures while LCVs with lower cross-linking density display obviously thermoresponsive size transition between 22 and 36 °C. The gelated LCVs exhibit enhanced permeability with temperature elevation and their permeabilities at different temperatures all elevate with increasing the cross-linking density.

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