Polymer Brushes Showing Non-Fouling in Blood Plasma Challenge the Currently Accepted Design of Protein Resistant Surfaces (pages 952–957)
Cesar Rodriguez-Emmenegger, Eduard Brynda, Tomas Riedel, Milan Houska, Vladimir Šubr, Aldo Bologna Alles, Erol Hasan, Julien E. Gautrot and Wilhelm T. S. Huck
Article first published online: 3 JUN 2011 | DOI: 10.1002/marc.201100189
Ultra-low-fouling biofunctionalizable poly‘ N-(2-hydroxypropyl) methacrylamide’ brushes are prepared for the first time. Similarly to the so far only ultra-low-fouling surface, poly(carboxybetaine acrylamide), they resisted the fouling from blood plasma, challenging the currently accepted views for the design of non-fouling surfaces. The antifouling properties of poly-‘N-(2-hydroxypropyl) methacrylamide’ are maintained after 24 months of storage.