Front Cover: A possible strategy to encrypt information at the molecular level is the creation of a binary code using two co-monomers defined as 0 and 1. As a proof of principle, sequence-defined oligo(triazole amide)s are synthesized via a stepwise solid-phase iterative process. In this approach, a reactive spacer, namely 1-amino-11-azido-3,6,9-trioxaundecane, is reacted with either 4-pentynoic acid (non-coding monomer) or 2-methyl-4-pentynoic acid (coding monomer). All possible information triads, 000, 001, 010, 100, 011, 101, 110, and 111 can be obtained using this approach. Further details can be found in the article by T. T. Trinh, L. Oswald, D. Chan-Seng, and J.-F. Lutz* on page 141.