This work presents a study about the hydrophilicity and conductivity of plasma polypyrroles (PPy) in contact with solutions of salt concentration similar to human tissues. PPy is a conjugated biocompatible polymer in which the electronic distribution produces partial relocation in contact with different compounds. PPy and PPy doped with iodine (PPy/I) particles of different sizes are being studied as implants in the central nervous system to restore the lost neuronal communication after severe injuries. Particle size, hydrophilicity and conductivity of these polymers are essential in this task. In this work, plasma PPy and PPy/I were synthesized as thin films using low-pressure, rf, resistive, electrical glow discharges and grounded up to obtain microparticles in the range of neuronal nuclei. The electrical conductivity of particles was studied with the addition of human-like ionic solutions, particularly with sodium and potassium ions which are part in the ionic transference of electric charges in neuronal membranes.