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Keywords:

  • biological action;
  • conformation;
  • small RNAs

Summary

Therapeutic RNAs have been strongly influencing the pharmaceutical market, which has been marked by capturing its part in last decade. Wide range of biological activities, production easiness and relative cheapness result in a powerful background for its mass production and implication in pharmacology. Their structure is known to be directly linked to the conformation they posses at given conditions. Conformational changes that may occur in response to various factors are believed to cause serious functional activity changes.