Diverse antimicrobial interactions of halophilic archaea and bacteria extend over geographical distances and cross the domain barrier
Version of Record online: 8 AUG 2013
© 2013 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 2, Issue 5, pages 811–825, October 2013
How to Cite
MicrobiologyOpen 2013; 2(5): 811–825
- Issue online: 8 OCT 2013
- Version of Record online: 8 AUG 2013
- Manuscript Accepted: 24 JUN 2013
- Manuscript Revised: 17 JUN 2013
- Manuscript Received: 7 NOV 2012
- Academy of Finland. Grant Numbers: 256518, 271413
- University of Helsinki
- Antimicrobial substances;
- halophilic archaea;
- halophilic bacteria;
The significance of antimicrobial substances, halocins, produced by halophilic archaea and bacteria thriving in hypersaline environments is relatively unknown. It is suggested that their production might increase species diversity and give transient competitive advances to the producer strain. Halocin production is considered to be common among halophilic archaea, but there is a lack of information about halocins produced by bacteria in highly saline environments. We studied the antimicrobial activity of 68 halophilic archaea and 22 bacteria isolated from numerous geographically distant hypersaline environments. Altogether 144 antimicrobial interactions were found between the strains and aside haloarchaea, halophilic bacteria from various genera were identified as halocin producers. Close to 80% of the interactions were detected between microorganisms from different genera and in few cases, even across the domain boundary. Several of the strains produced halocins with a wide inhibitory spectrum as has been observed before. Most of the antimicrobial interactions were found between strains from distant sampling sites indicating that hypersaline environments around the world have similar microorganisms with the potential to produce wide activity range antimicrobials.