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Keywords:

  • Acidocalcisomes;
  • Campylobacterales ;
  • chemoreceptors;
  • cryoelectron tomography;
  • cryo-EM;
  • food poisoning;
  • polyphosphate storage granules

Abstract

Campylobacter jejuni is one of the most successful food-borne human pathogens. Here we use electron cryotomography to explore the ultrastructure of C. jejuni cells in logarithmically growing cultures. This provides the first look at this pathogen in a near-native state at macromolecular resolution (~5 nm). We find a surprisingly complex polar architecture that includes ribosome exclusion zones, polyphosphate storage granules, extensive collar-shaped chemoreceptor arrays, and elaborate flagellar motors.