Analysis of periplasmic sensor domains from Anaeromyxobacter dehalogenans 2CP-C: Structure of one sensor domain from a histidine kinase and another from a chemotaxis protein (pages 766–777)
P. Raj Pokkuluri, Jeff Dwulit-Smith, Norma E. Duke, Rosemarie Wilton, Jamey C. Mack, Jessica Bearden, Ella Rakowski, Gyorgy Babnigg, Hendrik Szurmant, Andrzej Joachimiak and Marianne Schiffer
Version of Record online: 30 JUL 2013 | DOI: 10.1002/mbo3.112
The Anaeromyxobacter dehalogenans CP-C genome codes for a large number of sensor histidine kinases (HK) and methyl accepting chemotaxis proteins (MCP); among these 23 HK and 11 MCP proteins have a sensor domain in the periplasm. These proteins most likely contribute to adaptation to the organism's surroundings. We predicted their three-dimensional folds and determined the structures of two of the periplasmic sensor domains by X-ray diffraction.