Research Article

MicroRNA-1322 regulates ECRG2 allele specifically and acts as a potential biomarker in patients with esophageal squamous cell carcinoma†‡§

  1. Tengfei Zhang1,
  2. Dan Zhao1,‖,
  3. Qiming Wang2,
  4. Xiying Yu1,
  5. Yaling Cui3,
  6. Liping Guo1,
  7. Shih Hsin Lu1,*

Article first published online: 7 FEB 2012

DOI: 10.1002/mc.21880

Additional Information

How to Cite

Zhang, T., Zhao, D., Wang, Q., Yu, X., Cui, Y., Guo, L. and Lu, S. H. (2012), MicroRNA-1322 regulates ECRG2 allele specifically and acts as a potential biomarker in patients with esophageal squamous cell carcinoma. Mol. Carcinog.. doi: 10.1002/mc.21880

Author Information

  1. 1

    State Key Laboratory of Molecular Oncology, Department of Etiology and Carcinogenesis, Cancer Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  2. 2

    Department of Internal Medicine, Henan Tumor Hospital, Zhengzhou University, Zhengzhou, China

  3. 3

    Medical Record Library of Medical Services, Henan Tumor Hospital, Zhengzhou University, Zhengzhou, China

  1. ‖

    Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland, USA.

*Department of Etiology and Carcinogenesis, Cancer Hospital and Institute, Chinese Academy of Medical Sciences, Beijing 100021, China.

  1. †

    Authorship: Tengfei Zhang and Dan Zhao performed microRNA-1322 related cell experiments, statistical and bioinformatics analysis and drafting of the manuscript; Qiming Wang helped with ESCC tissue and serum sample collection and processing; Xiying Yu provided quantitative RT-PCR of microRNA technical support; Yaling Cui in sample and clinical pathological data collection; Liping Guo in study supervision; Shih Hsin Lu conducted the study design.

  2. ‡

    Each author approved the final version of the manuscript.

  3. §

    This project was approved by the Ethics Committee of Henan Tumor Hospital (Henan, China) on January 9th, 2008.

  4. This work had taken a poster presentation (Poster session A23) in the “Ninth Annual International Conference on Frontiers in Cancer Prevention Research” (November 7–10, 2010, Philadelphia, USA) and got the Scholar-in-Training Award supported by Susan G. Komen for the Cure®.

Publication History

  1. Article first published online: 7 FEB 2012
  2. Manuscript Accepted: 10 JAN 2012
  3. Manuscript Revised: 29 DEC 2011
  4. Manuscript Received: 4 AUG 2011

Funded by

  • National Natural Science Foundation Grant (China). Grant Number: 30971448
  • State Key Basic Research Program Grant (China). Grant Number: 2009CB521803
  • Chinese High-Tech R&D program Grant (China). Grant Number: 2006AA02A403

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