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Microelectrode recordings in the pallidum

Authors

  • Andres M. Lozano MD, PhD, FRCS(C),

    Corresponding author
    1. Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario, Canada
    • Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
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  • William D. Hutchison PhD

    1. Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario, Canada
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Abstract

The internal segment of the globus pallidus (GPi) is being targeted in neurosurgical procedures to treat Parkinson's disease and dystonia. Precise targeting of the pallidal complex is important in determining the efficacy of the surgical intervention and for the avoidance of adverse effects. Intraoperative microelectrode recording can be used to characterize the patterns of activity and receptive field properties of single pallidal neurons and to identify important bordering structures, including the optic tract and internal capsule. Because the clinical features of movement disorders can be differentially affected as a function of location within the pallidal complex, further refinements in intraoperative targeting may become important. © 2002 Movement Disorder Society

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