Delineating the sites and progression of in vivo atrophy in multiple system atrophy using fluid-registered MRI



We describe the pattern and progression of atrophy delineated using fluid registration of serial magnetic resonance imaging scans in a case of multiple system atrophy (MSA). The in vivo findings were consistent with those found at postmortem, including significant supratentorial atrophy concurrent with an unusual degree of cognitive impairment for MSA. © 2003 Movement Disorder Society