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Paroxysmal exercise-induced dystonia as a presenting feature of young-onset Parkinson's disease

Authors

  • Maria Bozi MD,

    1. Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, United Kingdom
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  • Kailash P. Bhatia FRCP

    Corresponding author
    1. Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, United Kingdom
    • Reader in Neurology, Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, United Kingdom
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Abstract

Paroxysmal exercise-induced dystonia (PED) is a rare, typically idiopathic familial condition, although sporadic and secondary cases have been reported. We present 2 cases where PED was the presenting feature of young-onset idiopathic Parkinson's disease (PD), preceding the onset of parkinsonian symptoms by 1.5 and 5 years, respectively. Initially, the dystonic symptoms occurred after prolonged exercise and were unilateral, affecting the foot in both patients. Over time, symptoms occurred with minimal exercise. We conclude that PED can rarely be the first and only feature of PD. © 2003 Movement Disorder Society

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