Clinical/Scientific Note

Rapidly progressive parkinsonism in a self-reported user of Ecstasy and other drugs †

  1. Padraig O'Suilleabhain MB, BCh1,*,
  2. Cole Giller MD, PhD2

Article first published online: 26 SEP 2003

DOI: 10.1002/mds.10623

Issue

Movement Disorders

Movement Disorders

Volume 18, Issue 11, pages 1378–1381, November 2003

Additional Information

How to Cite

O'Suilleabhain, P. and Giller, C. (2003), Rapidly progressive parkinsonism in a self-reported user of Ecstasy and other drugs . Movement Disorders, 18: 1378–1381. doi: 10.1002/mds.10623

Author Information

  1. 1

    Department of Neurology, University of Texas Southwestern Medical School, Dallas, Texas, USA

  2. 2

    Department of Neurosurgery, University of Texas Southwestern Medical School, Dallas, Texas, USA

*5323 Harry Hines Blvd., Dallas TX 75390-9036

  1. †

    A videotape accompanies this article.

Publication History

  1. Issue published online: 11 NOV 2003
  2. Article first published online: 26 SEP 2003
  3. Manuscript Accepted: 18 JUN 2003
  4. Manuscript Revised: 13 JUN 2003
  5. Manuscript Received: 21 OCT 2002

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Keywords:

  • parkinsonism;
  • MDMA;
  • drug use;
  • young onset

Abstract

A 38-year-old man developed parkinsonism that progressed to Hoehn and Yahr stage 5 within 4 years of onset. Response to ropinirole deteriorated, levodopa was not tolerated, and subthalamic nucleus stimulation has provided only partial relief of symptoms. He reported heavy use of Ecstasy through most of his twenties and thirties. His neurological problems may be unrelated to his drug use, but it is also possible they represent an idiosyncratic reaction. © 2003 Movement Disorder Society

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