Get access

Abnormalities of the spatiotemporal characteristics of gait at the onset of freezing in Parkinson's disease

Authors

  • Alice Nieuwboer PhD,

    Corresponding author
    1. Department of Rehabilitation Sciences of the Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Belgium
    • Department of Rehabilitation Sciences, Faculty of Physical Education and Physiotherapy, Tervuursevest 101, 3001 Heverlee, Belgium
    Search for more papers by this author
  • René Dom MD,

    1. Department of Rehabilitation Sciences of the Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Belgium
    Search for more papers by this author
  • Willy De Weerdt PhD,

    1. Department of Rehabilitation Sciences of the Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Belgium
    Search for more papers by this author
  • Kaat Desloovere PhD,

    1. Department of Rehabilitation Sciences of the Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Belgium
    Search for more papers by this author
  • Steffen Fieuws MSc,

    1. Department of Rehabilitation Sciences of the Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Belgium
    Search for more papers by this author
  • Eva Broens-Kaucsik MSc

    1. Department of Rehabilitation Sciences of the Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Belgium
    Search for more papers by this author

Abstract

We investigated the spatiotemporal variables of gait leading up to freezing. Gait analysis was carried out on 14 patients with Parkinson's disease in the off phase of the medication cycle. A computerised, three-dimensional gait analysis system was used to measure the walking pattern. After several trials of normal walking with voluntary stopping, distracting manoeuvres and obstacles on the walkway were used to provoke freezing or festination. The gait variables of normal (off phase), festinating, prestop, and prefreezing strides were analysed using analysis of variance for repeated-measures. Cadence was excessively increased (68%) and stride length decreased (69%) during festination compared with normal off walking; a pattern which remained pronounced when comparing prefreezing strides with normal stopping. Analysing in more detail the three steps before a freeze, we found a progressive decrease of stride length and stable cadence rates and proportions of double support phases. The relationship between cadence and stride length exhibited an exponential increase of cadence with a decreasing stride length during festination and freezing. Results suggest that freezing is caused by a combination of an increasing inability to generate stride length superimposed on a dyscontrol of the cadence of walking. © 2001 Movement Disorder Society.

Get access to the full text of this article

Ancillary