Intracortical inhibition is reduced in a patient with a lesion in the posterolateral thalamus


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We describe a patient who developed a complex movement disorder following an ischemic lesion in the right posterolateral thalamus. Transcranial magnetic stimulation showed a shortening of the cortical silent period and deficient cortico-cortical inhibition using paired magnetic pulses on the affected side, indicating reduced effectiveness of intracortical inhibitory mechanisms. © 2001 Movement Disorder Society.