Development of Parkinson's disease in patients with blepharospasm

Authors

  • Federico Micheli MD,

    Corresponding author
    1. Programa de Parkinson y Movimientos Anormales. Instituto de Neurociencias, Hospital de Clínicas “José de San Martín,” Buenos Aires, Argentina
    • Juncal 1695- P 5 Dpto J (1062), Buenos Aires, Argentina
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  • María Clara Scorticati MD,

    1. Programa de Parkinson y Movimientos Anormales. Instituto de Neurociencias, Hospital de Clínicas “José de San Martín,” Buenos Aires, Argentina
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  • Silvia Folgar MD,

    1. Programa de Parkinson y Movimientos Anormales. Instituto de Neurociencias, Hospital de Clínicas “José de San Martín,” Buenos Aires, Argentina
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  • Emilia Gatto MD

    1. Programa de Parkinson y Movimientos Anormales. Instituto de Neurociencias, Hospital de Clínicas “José de San Martín,” Buenos Aires, Argentina
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Abstract

The liability to develop parkinsonian symptoms was evaluated in 105 outpatients with idiopathic blepharospasm (IBS; 54 cases) or IBS associated to oromandibular dystonia (Meige's syndrome; 51 cases) mean age 70.3 ± 9.6 years, and compared with an age- and sex-matched population. Eleven patients developed Parkinson's disease in the blepharospasm group, whereas only 2 of 105 patients were affected in the control group. Our results suggest that patients with IBS either isolated or associated with oromandibular dystonia are more prone to develop parkinsonian symptoms. © 2004 Movement Disorder Society

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