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Machado–Joseph shoe

Authors

  • Chin San Liu MD, PhD,

    Corresponding author
    1. Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan
    2. Vascular and Genomic Research Center, Changhua Christian Hospital, Changhua, Taiwan
    3. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
    • Vascular and Genomic Center, Department of Neurology, Changhua Christian Hospital, 135 Nanhsiao Street, Changhua, Taiwan, 500, R.O.C.

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  • Mingli Hsieh PhD,

    1. Department of Biology, Tunghai University, Taichung, Taiwan
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  • Yi Yun Chen MSc,

    1. Vascular and Genomic Research Center, Changhua Christian Hospital, Changhua, Taiwan
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  • Man Chi Lo MD

    1. Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan
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Abstract

Machado–Joseph shoe (MJS), defined as a shoe/slipper with a deep hallux imprint at its base, and hyperostosis/osteoma toe were two early ataxic signs in 17 of 31 patients (55%) and 24 of 31 patients (77%) with Machado–Joseph disease (MJD), respectively. The MJS plus hyperostosis/osteoma toes may be helpful in the diagnosis of MJD in a patient during early truncal ataxia. © 2004 Movement Disorder Society

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