Levodopa-responsive parkinsonism associated with hydrocephalus



We report on a patient who developed acute parkinsonian symptoms following shunt revision for hydrocephalus. Parkinsonism improved dramatically after levodopa therapy. Furthermore, there was no recurrence of Parkinsonism despite discontinuation of levodopa. This observation suggests that Parkinsonism in this patient was caused by reversible dysfunction of the presynaptic nigrostriatal dopaminergic pathway due to hydrocephalus. © 2006 Movement Disorder Society