Botulinum toxin as a treatment for tardive dyskinesia

Authors

  • Peter N. van Harten MD, PhD,

    Corresponding author
    1. Symfora Group Psychiatric Center, Amersfoort, The Netherlands
    2. Meander General Hospital, Amersfoort, The Netherlands
    • Symfora group, Psychiatric Center, P.O. Box 3051, 3800DB Amersfoort, The Netherlands
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  • Ad Hovestadt MD, PhD

    1. Symfora Group Psychiatric Center, Amersfoort, The Netherlands
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Abstract

Two older female patients with a history of psychotic depression were treated with a combination of an antipsychotic and an antidepressant. Both developed persistent tardive dyskinesia with severe tongue protrusion. Botulinum toxin was injected into the genioglossal area and the embarrassing tongue protrusion practically disappeared. Both patients chose to continue taking botulinum toxin. © 2006 Movement Disorder Society

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