Research Article
Minimal clinically important change on the unified Parkinson's disease rating scale
Article first published online: 3 MAY 2006
DOI: 10.1002/mds.20914
Copyright © 2006 Movement Disorder Society
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How to Cite
Schrag, A., Sampaio, C., Counsell, N. and Poewe, W. (2006), Minimal clinically important change on the unified Parkinson's disease rating scale. Mov. Disord., 21: 1200–1207. doi: 10.1002/mds.20914
Publication History
- Issue published online: 22 AUG 2006
- Article first published online: 3 MAY 2006
- Manuscript Accepted: 6 JAN 2006
- Manuscript Revised: 28 DEC 2005
- Manuscript Received: 14 AUG 2005
- Abstract
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- 3, , , , Postural Instability in Patients with Parkinson’s Disease, CNS Drugs, 2013, 27, 2, 97
- 4, , , , , , , , , Success rate, efficacy, and safety/tolerability of overnight switching from immediate- to extended-release pramipexole in advanced Parkinson's disease, European Journal of Neurology, 2013, 20, 1Direct Link:
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- 6, , , , , , , , , Comparison of chocolate to cacao-free white chocolate in Parkinson’s disease: a single-dose, investigator-blinded, placebo-controlled, crossover trial, Journal of Neurology, 2012, 259, 11, 2447
- 7, , , Disease progress and response to treatment as predictors of survival, disability, cognitive impairment and depression in Parkinson's disease, British Journal of Clinical Pharmacology, 2012, 74, 2Direct Link:
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- 10, , , Indirect meta-analysis of randomised placebo-controlled clinical trials on rasagiline and selegiline in the symptomatic treatment of Parkinson’s disease, Basal Ganglia, 2012, 2, 4, S17
- 11
- 12, , , , , Nonmotor versus motor symptoms: How much do they matter to health status in Parkinson's disease?, Movement Disorders, 2012, 27, 2Direct Link:
- 13, , Progression of motor symptoms in Parkinson’s disease, Neuroscience Bulletin, 2012, 28, 1, 39
- 14, , , , , , , Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms, Parkinson's Disease, 2012, 2012, 1
- 15, , , Caffeine in Parkinson's disease: A pilot open-label, dose-escalation study, Movement Disorders, 2011, 26, 13Direct Link:
- 16, , Controversies in Neurology: why monoamine oxidase B inhibitors could be a good choice for the initial treatment of Parkinson's disease, BMC Neurology, 2011, 11, 1, 112
- 17, , Determination of minimal clinically important change in early and advanced Parkinson's disease, Movement Disorders, 2011, 26, 5Direct Link:
- 18, , Determining the Efficacy of Rasagiline in Reducing Bradykinesia Among Parkinson's Disease Patients: A Review, International Journal of Neuroscience, 2011, 121, 9, 485
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- 20, , , , , , Effects of a Flexibility and Relaxation Programme, Walking, and Nordic Walking on Parkinson's Disease, Journal of Aging Research, 2011, 2011, 1
- 21, , , Increases of pentraxin 3 plasma levels in patients with Parkinson's disease, Movement Disorders, 2011, 26, 13Direct Link:
- 22, , , , , , Measurement of patient-centered outcomes in Parkinson’s disease: What do patients really want from their treatment?, Parkinsonism & Related Disorders, 2011, 17, 2, 89
- 23, , , , , , Medication Responsiveness of Motor Symptoms in a Population-Based Study of Parkinson Disease, Parkinson's Disease, 2011, 2011, 1
- 24, , , Milestones in movement disorders clinical trials: Advances and landmark studies, Movement Disorders, 2011, 26, 6Direct Link:
- 25, , , , , , Should treatment for Parkinson's disease start immediately on diagnosis or delayed until functional disability develops?, Movement Disorders, 2011, 26, 7Direct Link:
- 26, , , , , , , , , Unilateral deep brain stimulation surgery in Parkinson’s disease improves ipsilateral symptoms regardless of laterality, Parkinsonism & Related Disorders, 2011, 17, 10, 745
- 27
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- 29, , , , , , , , , , , , Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial, The Lancet Neurology, 2010, 9, 6, 581
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- 35, , , , , , Double-blind trial of levodopa/carbidopa/entacapone versus levodopa/carbidopa in early Parkinson's disease, Movement Disorders, 2009, 24, 4Direct Link:
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- 49, , , , , , , , , , , Physiotherapy versus placebo or no intervention in Parkinson's disease, The Cochrane Library,Direct Link:
- 50, , , , , , , , , , , Physiotherapy versus placebo or no intervention in Parkinson's disease, The Cochrane Library,Direct Link:
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