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This article includes Supplementary Video, available online at http://www.interscience.wiley.com/jpages/0885-3185/suppmat

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jws-mds.21021.mpg12823K At the preoperative baseline, this 21-year-old man (Patient 1) with the DYT1 mutation manifested severe generalized dystonia. After 2 weeks of continuous stimulation of the bilateral globus pallidus internus, his dystonic symptoms were markedly alleviated. On the Burke-Fahn-Marsden Dystonia Rating Scale, his motor score improved by 91.2%.

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