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Keywords:

  • juvenile-onset Parkinsonism;
  • nicotine;
  • sensitivity

Abstract

We describe a patient with juvenile levodopa-responsive Parkinsonism who reported a dramatic response to cigarette smoking with transient but marked improvement of motor symptoms associated with oculogyric crises and psychotic behavior. His beta-CIT single-photon emission computed tomography scan showed a complete absence of presynaptic dopaminergic nerve terminals. © 2006 Movement Disorder Society