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mds21938.mpg14210KSegment 1. The 56-year-old proband, 8 years after the onset of neurological symptoms, is incapable of standing and walking and shows apathy and facial hypomimia. Moreover, he is affected by irregular postural, kinetic, and resting tremor of the upper limbs as evaluated while maintaining antigravity posture, the finger-nose-finger test, and at rest. It is also evident dystonic posture of the right hand and bradykinesia during the finger tap test. Segment 2. The 53-year-old proband's sister has evident neurological abnormalities limited to mild akinetic signs (facial hypomimia, reduced right arm swing during walking).

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