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Distribution of motor impairment influences quality of life in Parkinson's disease

Authors

  • Kim C. Stewart MS,

    1. Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, USA
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  • Hubert H. Fernandez MD,

    1. Movement Disorders Center, University of Florida, Gainesville, Florida, USA
    2. Department of Neurology, University of Florida, Gainesville, Florida, USA
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  • Michael S. Okun MD,

    1. Movement Disorders Center, University of Florida, Gainesville, Florida, USA
    2. Department of Neurology, University of Florida, Gainesville, Florida, USA
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  • Charles E. Jacobson BS,

    1. Department of Neurology, University of Florida, Gainesville, Florida, USA
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  • Chris J. Hass PhD

    Corresponding author
    1. Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, USA
    2. Movement Disorders Center, University of Florida, Gainesville, Florida, USA
    • Department of Applied Physiology and Kinesiology, University of Florida, Florida Gym Room 151, Gainesville, Florida 32611
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Abstract

We evaluated the relationship between upper extremity (UE) and lower extremity (LE) motor impairments in Parkinson's disease (PD) to overall disability and quality of life (QoL) measures. A total of 639 patients who were diagnosed with idiopathic PD were administered the Unified Parkinson's Disease Rating Scale (UPDRS), QoL, activities of daily living (ADL), and behavioral scales. Composite UE and LE scores from the motor section of the UPDRS were correlated with ADL, QoL, and behavioral measurement scores while controlling for disease duration. Patients with greater UE and LE motor impairments had lower QoL scores. However, LE impairments had a greater influence than UE impairments across all QoL measures. © 2008 Movement Disorder Society

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