Potential conflict of interest: None reported.
Article first published online: 21 OCT 2008
Copyright © 2008 Movement Disorder Society
Volume 24, Issue 1, pages 64–71, 15 January 2009
How to Cite
Morris, M. E., Iansek, R. and Kirkwood, B. (2009), A randomized controlled trial of movement strategies compared with exercise for people with Parkinson's disease. Mov. Disord., 24: 64–71. doi: 10.1002/mds.22295
This trial has been registered with the Australian Clinical Trials Register, number 8221.
- Issue published online: 23 JAN 2009
- Article first published online: 21 OCT 2008
- Manuscript Accepted: 31 JUL 2008
- Manuscript Revised: 14 JUL 2008
- Manuscript Received: 18 APR 2008
- Parkinson's disease;
This randomized controlled clinical trial was conducted to compare the effects of movement rehabilitation strategies and exercise therapy in hospitalized patients with idiopathic Parkinson's disease. Participants were randomly assigned to a group that received movement strategy training or musculoskeletal exercises during 2 consecutive weeks of hospitalization. The primary outcome was disability as measured by the Unified Parkinson's Disease Rating Scale, UPDRS (motor and ADL components). Secondary outcomes were balance, walking speed, endurance, and quality of life. Assessments were carried out by blinded testers at baseline, after the 2 weeks of treatment and 3 months after discharge. The movement strategy group showed improvements on several outcome measures from admission to discharge, including the UPDRS, 10 m walk, 2 minute walk, balance, and PDQ39. However, from discharge to follow up there was significant regression in performance on the 2 minute walk and PDQ39. For the exercise group, quality of life improved significantly during inpatient hospitalization and this was retained at follow-up. Inpatient rehabilitation produces short term reductions in disability and improvements in quality of life in people with Parkinson's disease. © 2008 Movement Disorder Society