Proposed neuroimaging criteria for the diagnosis of multiple system atrophy


  • Potential conflict of interest: DJB works for GE health care. KS has no disclosure.

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In this article, we review the state of the art knowledge concerning structural and functional imaging in multiple system atrophy (MSA). The relative value of imaging modalities in the differential diagnosis of MSA from other parkinsonian syndromes is debated. It is concluded that, although neuroimaging biomarkers provide valuable supportive data alongside clinical assessments, it is not possible to use them as surrogate markers. © 2009 Movement Disorder Society