Get access

Repeatable battery for assessment of neuropsychological status in early Parkinson's disease

Authors

  • Chengwu Yang MD, MS,

    1. Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina
    Search for more papers by this author
  • Elizabeth Garrett-Mayer PhD,

    1. Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina
    2. Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina
    Search for more papers by this author
  • Jay S. Schneider PhD,

    1. Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania
    Search for more papers by this author
  • Stephen M. Gollomp MD,

    1. Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania
    2. Lankenau Hospital, Wynnewood, Pennsylvania
    Search for more papers by this author
  • Barbara C. Tilley PhD

    Corresponding author
    1. Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina
    • 135 Cannon Street, Suite 303Q, Charleston, SC 29425
    Search for more papers by this author

  • Potential conflict of interest: None reported.

Abstract

Adequate reliability and valid factor structure are prerequisites for appropriate use of a measure in a population. Although the Repeatable Battery for Assessment of Neuropsychological Status (RBANS) has been used to examine cognition in Parkinson's disease (PD), its reliability and factor structure have not been examined in this population. This study examined the reliability and factor structure of the RBANS in participants with de novo PD recruited for two NIH Exploratory Trials in Parkinson's Disease (NET-PD), using Cronbach's α and factor analysis. Confirmatory factor analysis (CFA) was implemented on the factor structure proposed in the RBANS manual, and exploratory factor analysis (EFA) was conducted to identify a valid factor structure given the proposed one was not supported. The RBANS exhibited poor reliability in participants with NET-PD. Cronbach's α ranged from 0.03 to 0.74 for the five domains and the full scale. CFA results indicated that the proposed factor structure in the RBANS manual was not supported in this sample. EFA identified a two-factor structure for six of the 12 RBANS items. Six items were eliminated due to low correlation with other items or severe ceiling effects. This new factor structure was validated by another CFA. The two domains have fair reliability. Cronbach's α ranged from 0.65 to 0.74 for the two factors in the two datasets. These results suggest that the current RBANS domain and total scores may not provide valid measurement of the neuropsychological status for patients with early PD. © 2009 Movement Disorder Society

Ancillary