Sleep disturbances in Parkinson's disease

Authors

  • Matthew Menza MD,

    Corresponding author
    1. Departments of Psychiatry, Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    2. Departments of Neurology, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    • Department of Psychiatry, Robert Wood Johnson Medical School, D207A, 671 Hoes Lane, Piscataway, New Jersey 08854
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  • Roseanne DeFronzo Dobkin PhD,

    1. Departments of Psychiatry, Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
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  • Humberto Marin MD,

    1. Departments of Psychiatry, Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
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  • Karina Bienfait PhD

    1. Departments of Psychiatry, Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
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  • Potential conflict of interest: Nothing to report.

Abstract

Sleep disturbances are very common in patients with PD and are associated with a variety of negative outcomes. The evaluation of sleep disturbances in these patients is complex, as sleep may be affected by a host of primary sleep disorders, other primary medical or psychiatric conditions, reactions to medications, aging or the neuropathophysiology of PD itself. In this article, we review the evaluation of the common disturbances of sleep seen in PD. This includes the primary sleep disorders, the interaction of depression and insomnia, the impact that medications for PD have on sleep, as well as the role of factors such as nocturia, pain, dystonia, akinesia, difficulty turning in bed, and vivid dreaming. The treatment of sleep disturbances in PD is largely unstudied but recommendations based on clinical experience in PD and research studies in other geriatric populations can be made. Important principles include, diagnosis, treating the specific sleep disorder or co-occurring disorder, and control of the motor aspects of PD. © 2010 Movement Disorder Society

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