Potential conflict of interest: Nothing to report.
Short-term attention and verbal fluency is decreased in restless legs syndrome patients†
Article first published online: 10 SEP 2010
Copyright © 2010 Movement Disorder Society
Volume 25, Issue 15, pages 2641–2648, 15 November 2010
How to Cite
Fulda, S., Beitinger, M. E., Reppermund, S., Winkelmann, J. and Wetter, T. C. (2010), Short-term attention and verbal fluency is decreased in restless legs syndrome patients. Mov. Disord., 25: 2641–2648. doi: 10.1002/mds.23353
- Issue published online: 10 NOV 2010
- Article first published online: 10 SEP 2010
- Manuscript Accepted: 23 JUN 2010
- Manuscript Revised: 23 APR 2010
- Manuscript Received: 11 MAR 2010
- restless legs syndrome;
- cognitive functioning;
- verbal fluency
Restless legs syndrome (RLS) is a frequent sleep-related movement disorder with disturbed sleep and quality of life. RLS patients complain about increased daytime sleepiness, but there are only few and inconsistent reports about cognitive functioning in this group. We compared cognitive performance of 23 unmedicated RLS patients to that of 23 healthy controls matched individually for age, gender, and educational level. Cognitive tasks were chosen to assess short-term attention, working memory, learning and memory, verbal fluency, and executive functioning. RLS patients performed worse than controls in the area of attention and verbal fluency, and performance in these tasks was associated with RLS severity, sleep quality, depression scores, and memory. There was no difference for working memory, memory, learning, cognitive flexibility, and abstract reasoning. We conclude that there is evidence for deficits in short-term attention and verbal fluency in RLS patients. © 2010 Movement Disorder Society.