Potential conflict of interest: Nothing to report.
Fatigue in Parkinson's disease: Prevalence and associated factors†
Article first published online: 25 OCT 2010
Copyright © 2010 Movement Disorder Society
Volume 25, Issue 14, pages 2456–2460, 30 October 2010
How to Cite
Beiske, A. G., Loge, J. H., Hjermstad, M. J. and Svensson, PhD, E. (2010), Fatigue in Parkinson's disease: Prevalence and associated factors. Mov. Disord., 25: 2456–2460. doi: 10.1002/mds.23372
- Issue published online: 25 OCT 2010
- Article first published online: 25 OCT 2010
- Manuscript Accepted: 5 JUL 2010
- Manuscript Revised: 13 APR 2010
- Manuscript Received: 4 MAR 2010
- chronic fatigue;
- associated factors;
- population based
The purpose of this study was to examine the prevalence of fatigue in Parkinson's disease (PD) patients and compare this to the general population. Factors associated with fatigue were investigated by linear regression. Fatigue was assessed by the fatigue questionnaire. The mean age of the 176 PD patients (41% women) was 69 years (range 35–90), and the mean UPDRSIII was 22.3 (SD 11.7). Fatigue levels (means) were significantly higher in PD patients compared with the general population; however, effect sizes were moderate for women for physical and total fatigue indicating clinically significant differences here only. Only female PD patients had more chronic fatigue than the general population. Fatigue was related to characteristics of PD but also to sleep disturbance, depression, and gender. This population-based study demonstrates that fatigue is a common symptom in PD patients, but compared with the general population, clinically significant differences were only found for female PD patients. © 2010 Movement Disorder Society.