Potential conflict of interest: Nothing to report.
Vestibular evoked myogenic potentials are intact in cervical dystonia†
Article first published online: 19 OCT 2010
Copyright © 2010 Movement Disorder Society
Volume 25, Issue 16, pages 2845–2853, 15 December 2010
How to Cite
Rosengren, S. M. and Colebatch, J. G. (2010), Vestibular evoked myogenic potentials are intact in cervical dystonia. Mov. Disord., 25: 2845–2853. doi: 10.1002/mds.23422
- Issue published online: 16 DEC 2010
- Article first published online: 19 OCT 2010
- Manuscript Accepted: 2 AUG 2010
- Manuscript Revised: 8 JUL 2010
- Manuscript Received: 16 MAR 2010
- subjective visual vertical;
Vestibular dysfunction has been reported in patients with cervical dystonia (CD), but it is still unclear whether the abnormalities occur as part of the CD syndrome or whether they arise from the abnormal posture and movement of the head. We compared vestibular-evoked myogenic potentials (VEMPs) recorded from the affected neck muscles (i.e., cervical VEMPs) with those recorded from muscles unaffected by the dystonia, the extraocular muscles (i.e., ocular VEMPs). We compared 21 patients and age-matched normal controls to investigate whether these short-latency reflexes are altered in CD. We also measured subjective visual horizontal (SVH). Seven patients had not received botulinum toxin treatment (naïve group), 10 were receiving regular injections (treatment group), and four had previously received treatment but had developed antibodies (antibody group). Both cervical and ocular VEMPs were present in the majority of patients and controls. For both reflexes, there were no significant differences between stimulation of the two sides of the head, between the treatment groups, or between the patients and controls. There was also no difference in degree of deviation of SVH between the groups. Our results showed that VEMPs can be reliably recorded from both the neck and extraocular muscles in patients with CD, even after long disease or treatment durations, and provide evidence for intact short-latency vestibular reflexes in CD. © 2010 Movement Disorder Society.