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MDS_23428_sm_SuppFig1.tif3587KSupporting Information Figure 1. The inverse correlation between IGF-1 serum levels and Basis Pons and Medulla Oblongata volumetries on MRI. Two patients with similar ages, disease duration and CAG expanded repeats were chosen as an example. (A) and (C) represent a fifty two year old man, with nine years of disease duration and 72 CAG repeats on MJD gene. (B) and (D) represent a fifty one year old woman, with thirteen years of disease duration and 71 CAG repeats on MJD gene. Bars indicate percent difference between the individual and the mean study population values of IGF-1 serum levels and MRI brainstem volumes.
MDS_23428_sm_SuppFig2.tif729KSupporting Information Figure 2. Total IGF-1 correlations with brainstem volumetries. IGF-1 serum levels simple correlation with (A) medulla oblongata and (B) basis of pons MRI volumetries.* p<0.05.

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