Novel mutations in the CYP7B1 gene cause hereditary spastic paraplegia

Authors

  • Li Cao MD,

    1. Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
    Search for more papers by this author
  • Qing-Zhou Fei MD,

    1. Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
    Search for more papers by this author
    • Li Cao and Qing-Zhou Fei contributed equally to this work.

  • Wei-Guo Tang MD,

    1. Department of Neurology, Zhoushan Hospital, Zhejiang Province, China; and
    Search for more papers by this author
  • Jian-Rong Liu MD,

    1. Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
    Search for more papers by this author
  • Lan Zheng MD,

    1. Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
    Search for more papers by this author
  • Qin Xiao MD,

    1. Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
    Search for more papers by this author
  • Song-Bin He MD,

    1. Department of Neurology, Zhoushan Hospital, Zhejiang Province, China; and
    Search for more papers by this author
  • Yi Fu MD,

    1. Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
    Search for more papers by this author
  • Sheng-Di Chen MD, PhD

    Corresponding author
    1. Department of Neurology and Institute of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
    2. Lab of Neurodegenerative Diseases and Key Laboratory of Stem Cell Biology, Institute of Health Science, Shanghai Institutes of Biological Sciences (SIBS), Chinese Academy of Science (CAS) and Shanghai Jiao Tong University School of Medicine, Shanghai, China
    • Lab of Neurodegenerative Diseases and Key Laboratory of Stem Cell Biology, Institute of Health Science, Shanghai Institutes of Biological Sciences (SIBS), Chinese Academy of Science (CAS) and Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Search for more papers by this author

  • This study was supported by grants from the National Program of Basic Research of China (2006cb500706, 2010CB945200), National Natural Scientific Fund of China (30700888, 30770732, 30872728, 30872729), Shanghai Key Discipline Program (S30202), and Program for Outstanding Medical Academic Leader of Shanghai (LJ 06003). Relevant conflicts of interest/financial disclosures: Nothing to report.

    Full financial disclosures and author roles may be found in the online version of this article.

No abstract is available for this article.

Ancillary