Relevant conflicts of interest/financial disclosures: Nothing to report.
Electrogastrographyc activity in Parkinson's disease patients with and without motor fluctuations†
Version of Record online: 26 MAY 2011
Copyright © 2011 Movement Disorder Society
Volume 26, Issue 9, pages 1736–1740, 1 August 2011
How to Cite
Albani, G., El Assawy, N., Cattaldo, S., De Gennaro, M., Gregorini, F., Pradotto, L. and Mauro, A. (2011), Electrogastrographyc activity in Parkinson's disease patients with and without motor fluctuations. Mov. Disord., 26: 1736–1740. doi: 10.1002/mds.23662
Full financial disclosures and author roles may be found in the online version of this article. This study was partially supported by the Italian Ministry of Health (project RFPS-2007-1-641398).
- Issue online: 9 AUG 2011
- Version of Record online: 26 MAY 2011
- Manuscript Accepted: 6 JAN 2011
- Manuscript Revised: 23 DEC 2010
- Manuscript Received: 7 JUL 2010
- Parkinson's disease;
- gastric myoelectrical activity;
- motor fluctuations;
- L-dopa plasmatic levels
Gastroenteric dysfunctions are very common in Parkinson's disease, but their relationship with dopaminergic response and motor fluctuations is still unclear. Electrogastrography is a noninvasive method for measuring gastric myoelectrical activity.
We evaluated the effects of levodopa intake on the motility of empty stomachs in Parkinson's disease patients with and without motor fluctuations.
The electrogastrography findings showed a normal pattern not influenced by levodopa intake, unrelated to plasmatic levodopa concentrations and to clinical parameters.
Our results suggest that at rest gastric activity of Parkinson's disease patients is normal and plasmatic levodopa variability is not influenced by gastric motility. © 2011 Movement Disorder Society