Additional Supporting Information may be found in the online version of this article.

MDS_23681_sm_suppfig1.tif2807KSupporting Figure 1 IO curves before and after BT injections. The mean MEP amplitude (±SEM) is given on the y-axis against the stimulus intensity given on the x-axis (in percentage of 1mV stimulus intensity). The IO curves measured before BT injections, 1 month after and 3 months after BT injections were not significantly different.
MDS_23681_sm_suppfig2.tif67KSupporting Figure 2 Effect of paired associative stimulation (rPAS) on motor evoked potential (MEP) amplitude before BT injections, 1 month and 3 months after BT injections. The graph shows the mean amplitude of the MEPs collected 0, 30 and 60 min after rPAS, expressed as a percentage of the baseline MEP size (before rPAS). rPAS produced similar amount of facilitation in APB and FDI muscle before BT injections. 1 month after BT injections response to rPAS was abolished in both muscles, while 3 months after BT it partially recovered in both APB and FDI. * p< 0.05.
MDS_23681_sm_suppfig3.tif62KSupporting Figure 3 SICI and ICF, in response to rPAS and BT injections. SICI at an ISI of 2ms and ICF at an ISI of 12 ms are unchanged in response to rPAS and after BT injections.

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.