Funding agencies: This study was funded by the Federation pour la Recherche sur le Cerveau (to I.A.), France Parkinson, and the Société Française de Recherche et de Médecine du Sommeil (to D.O.).
Article first published online: 15 DEC 2011
Copyright © 2011 Movement Disorder Society
Volume 27, Issue 3, pages 428–431, March 2012
How to Cite
Oudiette, D., Leu-Semenescu, S., Roze, E., Vidailhet, M., De Cock, V. C., Golmard, J.-L. and Arnulf, I. (2012), A motor signature of REM sleep behavior disorder. Mov. Disord., 27: 428–431. doi: 10.1002/mds.24044
Relevant conflicts of interest/financial disclosures: Nothing to report.
Full financial disclosures and author roles may be found in the online version of this article.
- Issue published online: 12 MAR 2012
- Article first published online: 15 DEC 2011
- Manuscript Accepted: 19 SEP 2011
- Manuscript Revised: 13 SEP 2011
- Manuscript Received: 6 JUL 2011
- REM sleep behavior disorder;
- movement disorder;
- Parkinson's disease;
The purpose of this study was to determine if there was a common pattern in movements during REM sleep behavior disorder (RBD).
We blindly compared video-monitored movements during RBD (n = 136 clips) and wakefulness/arousal (n = 53 clips) in patients with Parkinson's disease (n = 29) and without parkinsonism (idiopathic RBD, n = 31; narcolepsy, n = 5).
The scorers accurately guessed the sleep/wake stage of 94% of video clips. Compared with wake movements, RBD movements were faster and more often repeated, jerky, and pseudohallucinatory, not self-centered, never associated with tremor, and rarely involved the environment in an appropriate manner. A specific posture of the hand (limp wrist with flexed digits) during grasping movements was evidenced during RBD in 48% of patients, reminiscent of hand-babbling in babies.
These characteristics of movements were found in the 3 conditions (Parkinson's disease, idiopathic RBD, and primary narcolepsy), delineating a common motor signature of RBD. © 2011 Movement Disorder Society