Relevant conflicts of interest/financial disclosures: Nothing to report.
Article first published online: 12 MAR 2012
Copyright © 2012 Movement Disorder Society
Volume 27, Issue 6, pages 690–695, May 2012
How to Cite
Shah, B. B. and Lang, A. E. (2012), Acquired neurosyphilis presenting as movement disorders. Mov. Disord., 27: 690–695. doi: 10.1002/mds.24950
Full financial disclosures and author roles may be found in the online version of this article.
- Issue published online: 30 MAY 2012
- Article first published online: 12 MAR 2012
- Manuscript Accepted: 19 JAN 2012
- Manuscript Revised: 5 JAN 2012
- Manuscript Received: 4 NOV 2011
- myoclonus, ataxia;
After a significant decline in the second half of the 20th century, rates of infection with syphilis are again on the rise. Long known as the “great mimicker,” syphilitic infection can be difficult to recognize clinically and this particularly holds true for neurologic manifestations of the disease. Gait dysfunction and sensory ataxia have been historically well described in neurosyphilis literature; however, other movement disorders have been reported to a lesser extent. Here we review reports of movement disorders in acquired neurosyphilis. Given its increasing incidence, it is important to be cognizant of its diverse presentation and retain a high index of suspicion for syphilis, particularly as it is completely curable in the early stages. © 2012 Movement Disorder Society