David R. Lynch, Steven M. Willi, and Robert B Wilson contributed equally to the present work.
Article first published online: 28 JUN 2012
Copyright © 2012 Movement Disorder Society
Volume 27, Issue 8, pages 1026–1033, July 2012
How to Cite
Lynch, D. R., Willi, S. M., Wilson, R. B., Cotticelli, M. G., Brigatti, K. W., Deutsch, E. C., Kucheruk, O., Shrader, W., Rioux, P., Miller, G., Hawi, A. and Sciascia, T. (2012), A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial. Mov. Disord., 27: 1026–1033. doi: 10.1002/mds.25058
Funding agencies: The in vitro work in the present study was funded by the Friedreich Ataxia Research Alliance (to R.B.W.) and Penwest Pharmaceutical. The clinical trial was sponsored by Penwest Pharmaceuticals.
Relevant conflicts of interest/financial disclosures: David R. Lynch and Steven M. Willi received grant support from Penwest Pharmaceutical to perform the present trial. David R. Lynch has also received support for clinical trials from Edison Pharmaceutical and Santhera Pharmaceutical and is an unpaid consultant to Apopharma and Lundbeck. Thomas Sciascia and Amale Hawi were employed by Penwest at the time of the study. Guy Miller and William Shrader hold stock in Edison Pharmaceuticals, the owner of EPI-A0001. Guy Miller is an employee and receives 100% of his compensation from Edison Pharmaceuticals. William Shrader is a compensated consultant for Edison Pharmaceuticals. Patrice Rioux was previously employed by Edison Pharmaceuticals.
Clinicaltrials.gov identifier: NCT01035671.
Full financial disclosures and author roles may be found in the online version of this article.
- Issue published online: 17 JUL 2012
- Article first published online: 28 JUN 2012
- Manuscript Accepted: 23 APR 2012
- Manuscript Revised: 23 MAR 2012
- Manuscript Received: 28 NOV 2011
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