Validation of a screening battery to predict driving fitness in people with Parkinson's disease

Authors


  • Funding agencies. This study was self-supported by the Department of Rehabilitation Sciences of KU Leuven and CARA, Belgian Road Safety Institute. Dr. Uc is supported by a Merit Review grant from Rehabilitation Research and Development Branch, US Department of Veterans Affairs.

  • Relevant conflicts of interest/financial disclosures: Nothing to report.

  • Full financial disclosures and author roles may be found in the online version of this article.

Correspondence to: Dr. Devos, KU Leuven, Faculty of Kinesiology and Rehabilitation Sciences, Department of Rehabilitation Sciences, Tervuursevest 101, BE-3001 Heverlee; hannes.devos@faber.kuleuven.be

ABSTRACT

Background

We previously developed a short clinical battery, consisting of contrast sensitivity, Clinical Dementia Rating, the Unified Parkinson's Disease Rating Scale-motor section (UPDRS III), and disease duration, which correctly classified 90% of drivers with Parkinson's Disease (PD). The aim of this study was to validate that screening battery in a different sample of PD drivers.

Methods

Sixty drivers with PD were enrolled to validate our original screening battery to predict driving fitness decisions (pass–fail) by a state agency where drivers underwent detailed visual, cognitive, and on-road testing.

Results

Twenty-four participants (40%) failed the driving evaluation. The screening battery correctly classified 46 (77%) participants (sensitivity and negative predictive value = 96%; specificity and positive predictive value = 64%). Adding other clinical predictors (e.g., age of onset, Hoehn-Yahr stage instead of UPDRS III) failed to improve the specificity of the model when the sensitivity was kept constant at 96%. However, a driving simulator evaluation improved the specificity of the model to 94%.

Conclusions

The original clinical battery proved to be a valid screening tool that accurately identifies fit drivers with PD and select those who need more detailed testing at specialized centers. © 2013 Movement Disorder Society

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