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Functional (psychogenic) symptoms in Parkinson's disease

Authors

  • Isabel Pareés MD,

    1. Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom
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    • Isabel Parés and Tabish A. Saifee contributed equally to this article.

  • Tabish A. Saifee MRCP,

    1. Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom
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    • Isabel Parés and Tabish A. Saifee contributed equally to this article.

  • Maja Kojovic MD,

    1. Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom
    2. Department of Neurology, University of Ljubljana, Ljubljana, Slovenia
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  • Panagiotis Kassavetis MD,

    1. Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom
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  • Ignacio Rubio-Agusti MD,

    1. Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom
    2. Movement Disorders Unit, Neurology Department, Hospital Universitari La Fe, Valencia, Spain
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  • Anna Sadnicka MRCP,

    1. Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom
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  • Kailash P. Bhatia MD, FRCP,

    1. Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom
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  • Mark J. Edwards MD, PhD

    Corresponding author
    1. Sobell Department of Motor Neuroscience and Movement Disorders, University College London (UCL) Institute of Neurology, London, United Kingdom
    • Correspondence to: Dr. Mark J. Edwards, Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, WC1N 3BG. United Kingdom; m.j.edwards@ucl.ac.uk

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  • Relevant conflicts of interest/financial disclosures: Nothing to report.

  • Full financial disclosures and author roles may be found in the online version of this article.

  • Funding agencies: Mark J. Edwards is funded by the National Institute for Health Research (NIHR) (6187). Isabel Pareés is funded by a Fundacion Alfonso Martin Escudero Grant. Tabish A. Saifee is funded by the NIHR. Anna Sadnicka is funded by the Guarantors of Brain with an Association of British Neurologists Clinical Training. This work was undertaken at UCL Hospital/UCL, which received a proportion of funding from the Department of Health's National Institute for Health Research Biomedical Research Centre funding scheme.

ABSTRACT

It has been reported that patients who have Parkinson's disease have a high prevalence of somatisation (functional neurological symptoms) compared with patients who have other neurodegenerative conditions. Numerous explanations have been advanced for this phenomenon. Here, with illustrative cases, we discuss this topic, including its clinical importance, and suggest a link between the pathophysiology of Parkinson's disease and the proposed propensity to develop functional symptoms. © 2013 International Parkinson and Movement Disorder Society

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