Framework for understanding balance dysfunction in Parkinson's disease

Authors

  • Bernadette Schoneburg MD,

    1. Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA
    2. Portland VA Medical Center, Portland, Oregon, USA
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  • Martina Mancini PhD,

    1. Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA
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  • Fay Horak PhD,

    1. Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA
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  • John G. Nutt MD

    Corresponding author
    1. Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA
    2. Portland VA Medical Center, Portland, Oregon, USA
    • Correspondence to: Dr. John G. Nutt, Professor of Neurology, Parkinson Center of Oregon, 3181 SW Sam Jackson Park Rd.w (OP32), Portland, OR 97239, USA; nuttj@ohsu.edu

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  • Funding agencies: This study has support from a PADRECC fellowship, the National Institute of Aging, the National Parkinson Foundation, the National Institute of Neurological Disorders and Stroke, and Ceregene.

  • Relevant conflicts of interest/financial disclosures: Fay Horak and OHSU have significant financial interests in APDM, a company that might have a commercial interest in the results of this research and technology. This potential conflict of interest has been reviewed and managed by OHSU and the Integrity Oversight Council. John Nutt serves as a consultant for Neuroderm Ltd, Merck, Elan Pharmaceuticals, Lundbeck Inc, ONO Pharma, SynAgile Crop, Prexa Inc, and US World Med and has received honoraria from the American Academy of Neurology.

  • Full financial disclosures and author roles may be found in the online version of this article.

ABSTRACT

People with Parkinson's disease (PD) suffer from progressive impairment in their mobility. Locomotor and balance dysfunction that impairs mobility in PD is an important cause of physical and psychosocial disability. The recognition and evaluation of balance dysfunction by the clinician are an essential component of managing PD. In this review, we describe a framework for understanding balance dysfunction in PD to help clinicians recognize patients who are at risk for falling and impaired mobility. © 2013 International Parkinson and Movement Disorder Society

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