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Additional Supporting Information may be found in the online version of this article.

FilenameFormatSizeDescription
aic14012-sup-0001-SuppInfo.docx11KSupporting Information
mds25641-sup-0002-suppFig1.eps13181KSupplementary Figure 1. Regional gray matter (A) and white matter (B) volume reduction in Parkinson's disease patients without visual hallucination compared to controls at a threshold of P < 0.001 (uncorrected). Volumetric values for the grey matter of PD-C patients were reduced significantly, particularly in the bilateral premotor cortex (BA 6), prefrontal cortex (BA 10), left precentral gyrus (BA 4), and right dorsolateral prefrontal cortex (BA 46) in the frontal lobe, and the right precuneus (BA 19), supramarginal gyrus (BA 40), and inferior parietal lobule (BA 39) in the parietal lobe; and in the left inferior temporal gyrus (BA 20) as compared to controls (Supplementary Fig. 1A and Supplementary Table 1). The volumetric values for the subcortical structures of PD-C patients were reduced significantly as compared to controls in the bilateral lentiform nucleus, right claustrum, left caudate, and white matter of the limbic lobe including the left parahippocampal (BA 23, 27, and 30) in the temporal lobe, bilateral precentral gyrus (BA6), left inferior frontal gyrus (BA 44 and 45), left precentral gyrus (BA 4) in the frontal lobe, and postcentral gyrus (BA 3) in the parietal lobe (Supplementary Fig. 1B and Supplementary Table 1).
mds25641-sup-0003-suppFig2.eps11689KSupplementary Figure 2. Regional gray matter (A) and white matter (B) volume reduction in Parkinson's disease patients with visual hallucination compared to controls at a threshold of P < 0.001 (uncorrected). The volumetric values for the grey matter of PD-VH patients was reduced widely and significantly compared to controls, particularly in the bilateral premotor cortex of the superior and middle frontal gyrus (BA 6 and 8), bilateral rostral part of prefrontal cortex (BA 10), left dorsolateral prefrontal cortex (BA 9), and left orbital frontal cortex (BA 47) in the frontal lobe; left secondary visual cortex of the inferior occipital and lingual gyrus (BA 18) in the occipital lobe (Supplementary Fig. 2A and Supplementary Table 2). The volumetric values for the subcortical structures of PD-VH patients were reduced significantly compared to controls in the right lateral geniculate body, bilateral lentiform nucleus, left claustrum, white matter of the left occipital lobe (BA 18 and 19), limbic lobe including bilateral parahippocampal (BA 19 and 36), cingulate (BA 31) gyrus, and left middle frontal gyrus (BA 8) (Supplementary Fig. 1B and Supplementary Table 2).
mds25641-sup-0004-suppTab1.docx143KSupplementary Table 1. Location and MNI coordinates of significant clusters of grey matter and white matter loss of Parkinson' s disease patients without visual hallucination (PD-C) compared with control
mds25641-sup-0005-suppTab2.docx143KSupplementary Table 2. Location and MNI coordinates of significant clusters of grey matter and white matter loss of Parkinson' s disease patients with visual hallucination (PD-VH) compared with control
mds25641-sup-0006-suppTab3.docx118KSupplementary Table 3 Location and MNI coordinates of significant clusters of grey matter and white matter loss of Parkinson' s disease patients with visual hallucination (PD-VH) compared with PD patients without VH (PD-C)

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