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mds25776-sup-0001-suppfig1.jpg53KSupplementary Figure 1: Semiquantitative AS-assessment Results of semiquantitative assessment of AS-aggregates in grouped areas of the CNS of all study subjects that include PD, DLB, AD and others. Grouped areas refer to “olfactory” (olfactory bulb and tract), “brainstem” (dorsal nucleus of vagus nerve, formatio reticularis, locus coeruleus, raphe, substantia nigra, periaqueductal gray matter, colliculi), “limbic” (amygdala, entorhinal and transentorhinal region, hippocampus, basal nucleus of Meynert, cingulum, insula), “cortical” (frontal, temporal, parietal and occipital cortex) and “spinal cord” (cervical, thoracic, lumbar). Semiquantitative assessment of AS density was performed as follows: 0: absent, 1: isolated or mild, 2: moderate, and 3: abundant
mds25776-sup-0002-suppfig2.jpg38KSupplementary Figure 2: Semiquantitative AS-assessment Semiquantitative assessment of AS density in different peripheral organs of PD and DLB cases. Each sign corresponds to an individual subject.
mds25776-sup-0003-supptab1.doc240KTable 1 Legend: Literature review of in vivo and postmortem studies of pANS involvement in Parkinson's disease (PD), incidental Lewy-body disease (iLBD) and dementia with Lewy bodies (DLB)

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