Relevant conflicts of interest/financial disclosures: Nothing to report.
Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits
Article first published online: 17 JAN 2014
© 2014 International Parkinson and Movement Disorder Society
Volume 29, Issue 4, pages 546–549, April 2014
How to Cite
Sarkar, S. N., Papavassiliou, E., Hackney, D. B., Alsop, D. C., Shih, L. C., Madhuranthakam, A. J., Busse, R. F., La Ruche, S. and Bhadelia, R. A. (2014), Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits. Mov. Disord., 29: 546–549. doi: 10.1002/mds.25808
Full financial disclosures and author roles may be found in the online version of this article.
- Issue published online: 3 APR 2014
- Article first published online: 17 JAN 2014
- Manuscript Accepted: 18 DEC 2013
- Manuscript Revised: 2 DEC 2013
- Manuscript Received: 7 MAY 2013
- conditional magnetic resonance imaging;
- deep brain stimulation;
- low specific absorption rate;
- radiofrequency heating;
- Parkinson's disease
For patients with deep brain stimulators (DBS), local absorbed radiofrequency (RF) power is unknown and is much higher than what the system estimates. We developed a comprehensive, high-quality brain magnetic resonance imaging (MRI) protocol for DBS patients utilizing three-dimensional (3D) magnetic resonance sequences at very low RF power.
Six patients with DBS were imaged (10 sessions) using a transmit/receive head coil at 1.5 Tesla with modified 3D sequences within ultra-low specific absorption rate (SAR) limits (0.1 W/kg) using T2, fast fluid-attenuated inversion recovery (FLAIR) and T1-weighted image contrast. Tissue signal and tissue contrast from the low-SAR images were subjectively and objectively compared with routine clinical images of six age-matched controls.
Low-SAR images of DBS patients demonstrated tissue contrast comparable to high-SAR images and were of diagnostic quality except for slightly reduced signal.
Although preliminary, we demonstrated diagnostic quality brain MRI with optimized, volumetric sequences in DBS patients within very conservative RF safety guidelines offering a greater safety margin. © 2014 International Parkinson and Movement Disorder Society