Parkinsonism following dystonia in three patients

Authors

  • Marc Katchen,

    1. UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey, U.S.A.
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  • Dr. Roger C. Duvoisin

    Corresponding author
    1. UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey, U.S.A.
    • UMDNJ-Robert Wood Johnson Medical School, Department of Neurology, 1 Robert Wood Johnson Place, New Brunswick, NJ 08903, U.S.A.
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Abstract

Three patients who presented initially with dystonia and subsequently developed typical idiopathic parkinsonism were evaluated: One patient presented with a writer's cramp, one with axial dystonia, and one with Meige syndrome. All three displayed amelioration of their dystonia with progression of their parkinsonism over a period of 2 to 15 years. Treatment with levodopa gave some relief of the parkinsonism symptoms in two patients but exacerbated or reactivated the dystonia. It is suggested that both the dystonia and the parkinsonism represent the changing clinical expression of the same disorder at different times in its evolution.

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